American Regent recalls nationwide supply of canine and equine Adequan after glass fibres found in samples

American Regent, Inc. has expanded its recall of Adequan products across the US following the detection of glass fibres in samples, raising concerns over quality control amid multiple recent withdrawals.

American Regent, Inc. Animal Health has expanded its recent recall activity with a nationwide withdrawal of two canine and two equine lots of Adequan, after glass fibres were found in retained samples during testing. The affected products are Adequan Canine Injection, used for dogs, and Adequan i.m. Injection, used in horses. No adverse events have been linked to the lots so far, according to the company’s notice posted by the US Food and Drug Administration.

The recall covers Adequan Canine lot numbers 25011 and 3369, and Adequan i.m. lots 24416 and 25265P. The company said the products were distributed across the US to online pharmacies, wholesalers, distributors and veterinarians between April 2025 and January 2026, depending on the lot. Both products are intramuscular, prescription-only joint therapies that should be administered by, or under the direction of, a licensed veterinarian.

American Regent warned that injecting a product containing particulate matter could cause local irritation, swelling, inflammation, pain at the injection site, infection or abscess formation. It asked consumers to stop using the affected stock and to contact their veterinarian if any animal has shown problems that may be related to treatment. Veterinary practices, hospitals and other holders of the product have been told to return unused vials or discard them, while distributors and retailers should halt sales immediately.

The FDA said the recall is being carried out with its knowledge. It comes just a week after the agency posted another American Regent recall involving papaverine hydrochloride injection over visible particulate matter identified as glass and/or paraformaldehyde, underscoring a wider quality-control problem at the company.

Image Source: American Regent